Nov. 12, 2014
Below are current clinical trials.1 studies in Tonsil cancer
(open studies only).
Filter this list of studies by location, status and more.
Jacksonville, Fla., Rochester, Minn., La Crosse, Wis., Albert Lea, Minn., Mankato, Minn.
RATIONALE: Giving radiation therapy that uses a 3-dimensional (3-D) image of the tumor to help focus thin beams of radiation directly on the tumor, and giving radiation therapy in higher doses over a shorter period of time, may kill more tumor cells and have fewer side effects. Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. It is not yet known whether radiation therapy is more effective when given alone or together with cetuximab in treating patients with head and neck cancer that has been removed by surgery.
PURPOSE: This randomized phase III trial is studying radiation therapy to see how well it works compared with radiation therapy given together with cetuximab in treating patients who have undergone surgery for locally advanced head and neck cancer.
- Flint PW, et al. Cummings Otolaryngology: Head & Neck Surgery. 5th ed. Philadelphia, Pa.: Mosby Elsevier; 2010. https://www.clinicalkey.com. Accessed Sept. 9, 2014.
- Shah JP, et al. Jatin Shah's Head and Neck Surgery and Oncology. 4th ed. Philadelphia, Pa: Mosby Elsevier; 2012. https://www.clinicalkey.com. Accessed Sept. 9, 2014.
- Oropharyngeal cancer treatment (PDQ). National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/oropharyngeal/HealthProfessional. Accessed Sept. 9, 2014.
- Head and neck cancer. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed Sept. 9, 2014.
- Cook AJ. Decision Support System. Mayo Clinic, Rochester, Minn. July 7, 2014.
- Moore EJ (expert opinion). Mayo Clinic, Rochester, Minnesota. Sept. 29, 2014.