Treatment for reactive thrombocytosis is directed at the underlying cause. If a recent surgery or an injury that caused significant blood loss is the cause, your elevated platelet count may not last long. If the cause is a chronic infection or an inflammatory disease, your platelet count may remain high until the condition is brought under control. In most cases, your platelet count will return to normal after the underlying cause is resolved.
Removal of your spleen may cause lifelong thrombocytosis. In that case, your doctor may prescribe low-dose aspirin to help prevent bleeding or blood-clotting incidents, although these occur rarely in reactive thrombocytosis.
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- Tefferi A. Approach to the patient with thrombocytosis. http://www.uptodate.com/index. Accessed Aug. 8, 2012.
- What are thrombocythemia and thrombocytosis? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/thrm/. Accessed Aug. 8, 2012.
- Tchebiner JZ, et al. Diagnostic and prognostic value of thrombocytosis in admitted medical patients. American Journal of the Medical Sciences. 2011;342:395.
- Skoda RC. Thrombocytosis. Hematology. 2009:159. http://asheducationbook.hematologylibrary.org/content/2009/1.toc. Accessed Aug. 8, 2012.
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