Treatment for reactive thrombocytosis is directed at the underlying cause. If a recent surgery or an injury that caused significant blood loss is the cause, your elevated platelet count may not last long. If the cause is a chronic infection or an inflammatory disease, your platelet count may remain high until the condition is brought under control. In most cases, your platelet count will return to normal after the underlying cause is resolved.
If you have reactive thrombocytosis, it is unlikely that you will need drugs or a medical procedure to lower your platelet count. It is also unlikely that you will experience blood clotting or bleeding.
Removal of your spleen (splenectomy) may cause lifelong thrombocytosis, but you are unlikely to need treatment.
July 10, 2015
- Tefferi A. Approach to the patient with thrombocytosis. http://www.uptodate.com/home. Accessed June 15, 2015.
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- Reactive thrombocytosis. Merck Manual Professional Edition. http://www.merckmanuals.com/professional/hematology-and-oncology/myeloproliferative-disorders/reactive-thrombocytosis-secondary-thrombocythemia. Accessed June 16, 2015.
- Sulai NH, et al. Why does my patient have thrombocytosis? Hematology/Oncology Clinics of North America. 2012;26:285.
- Kitchens CS, et al. Thrombocytosis. In: Consultative Hemostasis and Thrombosis. 3rd ed. Philadelphia, Pa.: Saunders Elsevier; 2013. http://www.clinicalkey.com. Accessed June 16, 2015.
- Mesa RA (expert opinion). Mayo Clinic, Phoenix/Scottsdale, Ariz. June 22, 2015.