Systemic capillary leak syndrome frequently causes complex medical problems involving many body systems. Episodes are typically sudden, although sometimes certain warning signs or symptoms can alert you.
An attack may include a marked drop in blood pressure. If not treated promptly, this can lead to multiple organ failure and death.
Treatment may include:
Nov. 26, 2014
- Fluids. You receive fluids intravenously, carefully controlled to maintain your blood pressure and prevent damage to vital organs, such as your kidneys, heart and brain.
- Medications. You may receive a prescription for steroids, water pills (diuretics), immunoglobulin or other drugs. You'll probably need to take medications long term to reduce the frequency and severity of future episodes.
- Druey KM, et al. Narrative review: The systemic capillary leak syndrome. Annals of Internal Medicine. 2010;153:90.
- Kapoor P, et al. Idiopathic systemic capillary leak syndrome (Clarkson's disease): The Mayo Clinic Experience. Mayo Clinic Proceedings. 2010;85:905.
- Riggin EA. Decision Support System. Mayo Clinic, Rochester, Minn. June 25, 2014.
- Gousseff M, et al. The systemic capillary leak syndrome: A case series of 28 patients from a European registry. Annals of Internal Medicine 2011;154:464.
- Xie Z, et al. Vascular endothelial hyperpermeability induces the clinical symptoms of Clarkson disease (the systemic capillary leak syndrome). Blood. 2012;119:4321.