Diagnosis at Mayo Clinic

By Mayo Clinic Staff

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Systemic capillary leak syndrome (SCLS) is difficult to diagnose. Diagnostic tests may include blood and urine tests and imaging studies. Doctors may diagnose sudden, periodic "attacks" of SCLS by detecting concentrated blood and low serum protein in the presence of certain signs and symptoms, such as generalized body swelling, muscle aches, lightheadedness, fatigue, shortness of breath and decreased urination — and by excluding other conditions that could cause these symptoms.

Nov. 20, 2012