Overview

Sweet's syndrome is a rare skin condition. Its main signs include fever and painful skin lesions that appear mostly on your arms, neck, head and trunk.

The exact cause of Sweet's syndrome isn't known. In some people, it's triggered by an infection, illness or certain medications. Sweet's syndrome can also occur with some types of cancer.

The most common treatment for Sweet's syndrome is corticosteroid pills, such as prednisone. Signs and symptoms often disappear just a few days after treatment begins, but recurrence is common.

Dec. 10, 2015
References
  1. Goldsmith LA, et al., eds. Acute febrile neutrophilic dermatosis. In: Fitzpatrick's Dermatology in General Medicine. 8th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com. Accessed Sept. 24, 2015.
  2. Herbert Cohen D, et al. Sweet's syndrome. The Journal of Emergency Medicine. 2015;49:e95.
  3. Rochet NM, et al. Sweet syndrome: Clinical presentation, associations, and response to treatment in 77 patients. Journal of the American Academy of Dermatology. 2013;69:557.
  4. Goldman L, et al., eds. Macular, popular, vesiculobullous and pustular diseases. In: Goldman-Cecil Medicine. 25th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. http://www.clinicalkey.com. Accessed Sept. 24, 2015.
  5. Merola, JF. Sweet syndrome (acute febrile neutrophilic dermatosis): Management and prognosis. http://www.uptodate.com/home. Accessed Sept. 24, 2015.
  6. Merola, JF. Sweet syndrome (acute febrile neutrophilic dermatosis): Pathogenesis, clinical manifestations, and diagnosis. http://www.uptodate.com/home. Accessed Sept. 24, 2015.
  7. Bolognia JL, et al. Neutrophilic dermatoses. In: Dermatology Essentials. Philadelphia, Pa.: Saunders Elsevier; 2014. http://www.clinicalkey.com. Accessed Sept. 29, 2015.
  8. Saag KG, et al. Major side effects of systemic glucocorticoids. http://www.uptodate.com/home. Accessed Sept. 24, 2015.