Treatment

Sweet's syndrome may go away without treatment. But medications can speed the process dramatically.

The most common medications used for Sweet's syndrome are corticosteroids, which come in a variety of forms, including:

  • Pills. Oral corticosteroids, such as prednisone, work very well but will affect your entire body. Unless you only have a few lesions, you'll likely need to take oral corticosteroids. Long-term use can cause side effects, such as weight gain, insomnia and weakened bones.
  • Creams or ointments. These preparations usually affect just the portion of skin where they're applied, but can cause thinning skin.
  • Injections. Another option is to inject a small amount of corticosteroid right into each lesion. This may be less feasible for people who have a great number of lesions.

Sometimes other medications are prescribed for Sweet's syndrome, usually for people who don't tolerate long-term corticosteroid use well. Some of the more commonly prescribed medication alternatives to corticosteroids are:

  • Dapsone
  • Potassium iodide
  • Colchicine (Colcrys, Mitigare)