Sweet's syndrome may go away without treatment. But medications can speed the process dramatically.
The most common medications used for Sweet's syndrome are corticosteroids, which come in a variety of forms, including:
- Pills. Oral corticosteroids, such as prednisone, work very well but will affect your entire body. Unless you only have a few lesions, you'll likely need to take oral corticosteroids. Long-term use can cause side effects, such as weight gain, insomnia and weakened bones.
- Creams or ointments. These preparations usually affect just the portion of skin where they're applied, but can cause thinning skin.
- Injections. Another option is to inject a small amount of corticosteroid right into each lesion. This may be less feasible for people who have a great number of lesions.
Sometimes other medications are prescribed for Sweet's syndrome, usually for people who don't tolerate long-term corticosteroid use well. Some of the more commonly prescribed medication alternatives to corticosteroids are:
- Potassium iodide
- Colchicine (Colcrys, Mitigare)