There's no cure for Stickler syndrome. Treatment addresses the signs and symptoms of the disorder.
- Pain relievers. Over-the-counter drugs such as ibuprofen (Advil, Motrin IB) and naproxen (Aleve) may help relieve joint swelling, stiffness and pain.
- Glaucoma drugs. Children who have glaucoma will need to take daily medications to control the pressure within their eyes. Most of these types of medications come in the form of eyedrops.
- Speech therapy. Your child may need speech therapy if hearing loss interferes with his or her ability to learn how to pronounce certain sounds.
- Physical therapy. In some cases, physical therapy may help with mobility problems associated with joint pain and stiffness. Equipment such as braces, canes and arch supports may also help.
- Hearing aids. If your child has problems hearing, you may find that his or her quality of life is improved by wearing a hearing aid.
- Special education. Hearing or vision problems may cause learning difficulty in school, so special education services may be helpful.
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- Tracheostomy. Newborns with very small jaws and displaced tongues may need a tracheostomy to create a hole in the throat so that they can breathe. The operation is reversed once the baby has grown large enough that his or her airway is no longer blocked.
- Jaw surgery. Surgeons can lengthen the lower jaw by breaking the jawbone and implanting a device that will gradually stretch the bone as it heals.
- Cleft palate repair. Babies born with a hole in the roof of the mouth (cleft palate) typically undergo surgery in which tissue from the roof of the mouth may be stretched to cover the cleft palate.
- Ear tubes. The surgical placement of a short plastic tube in the eardrum can help reduce the frequency and severity of ear infections, which are especially common in children who have Stickler syndrome.
- Eye surgeries. Surgeries to remove cataracts or procedures to reattach the lining of the back of the eye (retina) may be necessary to preserve vision.
- Joint replacement. Early onset arthritis, particularly in the hips and knees, may necessitate joint replacement surgeries at a much younger age than is typical for the general population.
- Kliegman RM, et al. Nelson Textbook of Pediatrics. 19th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/das/book/body/208746819-6/0/1608/0.html. Accessed May 29, 2013.
- Snead MP, et al. Stickler syndrome, ocular-only variants and a key diagnostic role for the ophthalmologist. Eye. 2011;25:1389.
- Couchouron T, et al. Early-onset progressive osteoarthritis with hereditary progressive ophthalmopathy or Stickler syndrome. Joint Bone Spine. 2010;78:45.
- Buchanan EP, et al. Syndromes with craniofacial abnormalities. http://www.uptodate.com/home. Accessed May 29, 2013.
- Pagon RA, et al. GeneReviews. Seattle, Wash.: University of Washington, Seattle; 2011. http://www.ncbi.nlm.nih.gov/books/NBK1302. Accessed May 30, 2013.
- Acke FR, et al. Hearing impairment in Stickler syndrome: A systematic review. Orphanet Journal of Rare Diseases. 2012;7:84.
- Michels VV (expert opinion). Mayo Clinic, Rochester, Minn. July 24, 2013.
- Daroff RB, et al. Bradley's Neurology in Clinical Practice. 6th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-1-4377-0434-1..C2009-0-40427-6--TOP&isbn=978-1-4377-0434-1&uniqId=364938937-2. Accessed May 29, 2013.
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