Small vessel disease is a condition in which the walls of the small arteries in the heart are damaged. The condition causes signs and symptoms of heart disease, such as chest pain (angina).
Small vessel disease is sometimes called coronary microvascular disease or small vessel heart disease. It's often diagnosed after a doctor finds little or no narrowing in the main arteries of your heart, despite your having symptoms that suggest heart disease.
Small vessel disease is more common in women and in people who have diabetes or high blood pressure. The condition is treatable but can be difficult to detect.
Aug. 22, 2017
- Coronary microvascular disease. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/book/export/html/4939. Accessed Jan. 21, 2016.
- Chaudhary I. Cardiac syndrome X: Angina pectoris with normal cardiac arteries. http://www.uptodate.com/home. Accessed Jan. 21, 2016.
- Crea F, et al. Coronary microvascular dysfunction: An update. European Heart Journal. 2014;35:1101.
- Lin CD, et al. Coronary microvascular function and beyond: The crosstalk between hormones, cytokines, and neurotransmitters. International Journal of Endocrinology. 2015;2015:1.
- Dean J, et al. Coronary microvascular dysfunction: Sex-specific risk, diagnosis and therapy. Nature Review Cardiology. 2015;12:406.
- Vizzardi E, et al. Noninvasive assessment of endothelial function: The classic methods and the new peripheral arterial tonometry. Journal of Investigative Medicine. 2014;62:856.
- Gerber TC, et al. Noninvasive coronary imaging with cardiac computed tomography and cardiovascular magnetic resonance. http://www.uptodate.com/home. Accessed Feb.1, 2016.