Selective IgA deficiency is an immune system condition in which you lack or don't have enough immunoglobulin A (IgA), a protein that fights infection (antibody). Most people with selective IgA deficiency don't have recurrent infections. However, some people who have IgA deficiency experience recurrent respiratory tract infections, asthma, sinus infections, allergies and diarrhea.

Selective IgA deficiency may also be found with autoimmune disease, in which your immune system attacks particular organs or tissues in your own body. Common autoimmune conditions found with IgA deficiency include rheumatoid arthritis, lupus and celiac disease.

  • Expertise. Mayo Clinic doctors trained in immune system disorders have experience in caring for people with selective IgA deficiency and other primary immunodeficiency conditions. The Primary Immunodeficiency Center at Mayo Clinic in Rochester, Minnesota, is a designated Jeffrey Modell Foundation Diagnostic and Research Center — a nonprofit organization that promotes and conducts research for primary immunodeficiency disorders.
  • Personalized care. Most people with selective IgA deficiency don't receive treatment unless they have recurrent infections. Your Mayo Clinic doctor will work closely with you to recognize and treat infections as soon as they occur. In some cases, you may need a long course of antibiotics to prevent an infection from returning.

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people. In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Doctors trained in allergy, asthma and clinical immunology care for adults with IgA deficiency at Mayo Clinic in Phoenix/Scottsdale, Arizona.

For appointments or more information, call the Central Appointment Office at 800-446-2279 (toll-free) 8 a.m. to 5 p.m. Mountain Standard Time, Monday through Friday or complete an online appointment request form.

Doctors trained in immune conditions and allergic diseases care for adults with IgA deficiency at Mayo Clinic in Jacksonville, Florida.

For appointments or more information, call the Central Appointment Office at 904-953-0853 8 a.m. to 5 p.m. Eastern time, Monday through Friday or complete an online appointment request form.

Doctors trained in immune conditions and allergic diseases in the Primary Immunodeficiency Center and other areas care for people with IgA deficiency at Mayo Clinic in Rochester, Minnesota.

507-538-3270
7 a.m. to 6 p.m. Central time, Monday through Friday

Doctors trained in pediatric immunodeficiency disorders, pediatrics, and pediatric allergy, immunology and pulmonary medicine care for children with IgA deficiency at Mayo Clinic in Rochester, Minnesota.

See information on patient services at the three Mayo Clinic locations, including transportation options and lodging.

Staff members in the Primary Immunodeficiency Center at Mayo Clinic in Rochester, Minnesota, conduct basic and clinical research in selective IgA deficiency and other primary immunodeficiency conditions.

See a list of publications by Mayo authors on PubMed, a service of the National Library of Medicine.

March 05, 2015