Often, there's no known cause for restless legs syndrome. Researchers suspect the condition may be due to an imbalance of the brain chemical dopamine, which sends messages to control muscle movement.

Heredity

Sometimes RLS/WED runs in families, especially if the condition starts before age 50. Researchers have identified sites on the chromosomes where genes for RLS/WED may be present.

Pregnancy

Pregnancy or hormonal changes may temporarily worsen RLS/WED signs and symptoms. Some women get RLS/WED for the first time during pregnancy, especially during their last trimester. However, signs and symptoms usually disappear after delivery.

Dec. 10, 2014

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