Often, there's no known cause for restless legs syndrome. Researchers suspect the condition may be due to an imbalance of the brain chemical dopamine, which sends messages to control muscle movement.


Sometimes RLS/WED runs in families, especially if the condition starts before age 50. Researchers have identified sites on the chromosomes where genes for RLS/WED may be present.


Pregnancy or hormonal changes may temporarily worsen RLS/WED signs and symptoms. Some women get RLS/WED for the first time during pregnancy, especially during their last trimester. However, signs and symptoms usually disappear after delivery.

Dec. 10, 2014