Research

Doctors at Mayo Clinic have a long-standing interest in research related to renal artery stenosis. Findings from research studies can lead to new and improved treatments. Current research efforts focus on:

  • Assessing the most effective renal artery stenosis treatments
  • Exploring how renal artery stenosis affects small vessels and kidney tissue injury
  • Developing imaging tools to better evaluate blood flow and injury in the kidney
  • Determining the most appropriate treatment for people who have high blood pressure caused by renal artery stenosis
  • Increasing recovery of kidney function after treatment
  • Exploring new methods of boosting kidney repair after restoring blood flow

Researchers at Mayo Clinic are studying new diagnostic tools such as the multidetector computerized tomography (CT) scan and blood oxygen level dependent (BOLD) magnetic resonance imaging (MRI). Mayo Clinic researchers developed these imaging tools, which use 3-D images to assess kidney function. BOLD MRI can show whether your kidney is getting sufficient oxygen and can recover after renal revascularization.

Current clinical trials underway include repair of injured kidney tissue with the administration of a person's own mesenchymal stem cells and the use of investigational protective agents (mitochondrial protection) at the time of revascularization.

Publications

See a list of publications on renal artery stenosis by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

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May 31, 2017
References
  1. Renal artery stenosis. National Kidney and Urologic Diseases Information Clearinghouse. https://www.niddk.nih.gov/health-information/kidney-disease/renal-artery-stenosis. Accessed March 1, 2017.
  2. Ferri FF. Renal artery stenosis. In: Ferri's Clinical Advisor 2017. Philadelphia, Pa.: Elsevier; 2017. https://www.clinicalkey.com. Accessed March 1, 2017.
  3. Chiang CE, et al. 2015 Guidelines of the Taiwan Society of Cardiology and the Taiwan Hypertension Society for the management of hypertension. Journal of the Chinese Medical Association. 2015;78:1.
  4. Skorecki K, et al., eds. Renovascular hypertension and ischemic nephropathy. In: Brenner & Rector's The Kidney. 10th ed. Philadelphia, Pa.: Elsevier; 2016. http://www.clinicalkey.com. Accessed March 1, 2017.
  5. Fibromuscular dysplasia (FMD). American Heart Association. http://www.strokeassociation.org/STROKEORG/StrokeConnectionMagazine/ReadSCNow/Fibromuscular-Dysplasia-FMD_UCM_461419_Article.jsp#.WLg4M1Xyt0w. Accessed March 2, 2017.
  6. Herrmann SM, et al. Management of atherosclerotic renovascular disease after Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL). Nephrology Dialysis Transplant. 2015;30:375.
  7. Managing weight to control high blood pressure. American Heart Association. http://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Weight-Management-and-Blood-Pressure_UCM_301884_Article.jsp#.WLhNUVXyt0w. Accessed March 2, 2017.
  8. Stress and heart health. American Heart Association. http://www.heart.org/HEARTORG/HealthyLiving/StressManagement/HowDoesStressAffectYou/Stress-and-Heart-Health_UCM_437370_Article.jsp#.WLhOvFXyt0w. Accessed March 2, 2017.
  9. Brown A. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Jan. 17, 2017.
  10. Textor SC (expert opinion). Mayo Clinic, Rochester, Minn. March 8, 2017.