Expertise and rankings

  • Team approach. Specialists trained in neurology, speech pathology and movement disorders work together to diagnose and treat people with progressive supranuclear palsy at Mayo Clinic.
  • Clinical experience. Progressive supranuclear palsy is very rare, affecting only three to six people in every 100,000 worldwide. Mayo Clinic doctors treat more than 400 people every year with this uncommon condition.
  • Advanced diagnosis. Mayo Clinic researchers discovered that some people with progressive supranuclear palsy develop speech problems (apraxia of speech) years before experiencing other symptoms. This speech problem may be the first sign of progressive supranuclear palsy. Mayo Clinic doctors also use specialized MRI and positron emission tomography (PET) to diagnose progressive supranuclear palsy.
  • Research leader. Mayo Clinic researchers are working to improve diagnosis and treatment of progressive supranuclear palsy.

    Specific efforts involve mapping changes in the brains of people with the condition, comparing familial and sporadic cases, using imaging to predict disease progression and to pinpoint diagnosis, and looking for environmental and genetic factors that may be associated with the condition.

    Mayo Clinic also has one of the largest progressive supranuclear palsy brain banks in the world.

Mayo Clinic in Rochester, Minn., ranks No. 1 for neurology and neurosurgery in the U.S. News & World Report Best Hospitals rankings. Mayo Clinic in Phoenix/Scottsdale, Ariz., and Mayo Clinic in Jacksonville, Fla., are ranked among the Best Hospitals for neurology and neurosurgery by U.S. News & World Report.