There's no cure for progeria, but regular monitoring for heart and blood vessel (cardiovascular) disease may help with managing your child's condition.
Certain therapies may ease or delay some of the signs and symptoms. They include:
- Low-dose aspirin. A daily dose may help prevent heart attacks and stroke.
- Other medications. Depending on your child's condition, the doctor may prescribe other medications, such as statins to lower cholesterol or anticoagulants to help prevent blood clots. The doctor may discuss the option of using growth hormone to help increase height and weight.
- Physical and occupational therapy. These therapies may help with joint stiffness and hip problems to help your child to remain active.
- Extraction of primary teeth. Your child's permanent teeth may start coming in before the baby (primary) teeth fall out. Pulling out some primary teeth may prevent overcrowding and encourage proper positioning of the permanent teeth.
Current research is being done to understand progeria and identify new treatment options. Some areas of research include:
May. 03, 2014
- Studying genes and the course of the disease to understand how it progresses. This may help identify new treatments.
- Performing human clinical trials using drugs known as farnesyltransferase inhibitors (FTIs), which were developed for treating cancer, but may be effective for treatment of progeria.
- Testing other drugs for treatment of progeria.
- Dorland's Illustrated Medical Dictionary. 32nd ed. Philadelphia, Pa.: W.B. Saunders; 2011. http://dorlands.com/index.jsp. Accessed Jan. 29, 2014.
- Learning about progeria. National Human Genome Research Institute. http://www.genome.gov/11007255. Accessed Jan. 29, 2014.
- Progeria (Hutchinson-Gilford syndrome). The Merck Manuals: The Merck Manual for Health Care Professionals. http://www.merckmanuals.com/professional/pediatrics/miscellaneous_disorders_in_infants_and_children/progeria.html. Accessed Jan. 29, 2014.
- Disorders of accelerated aging. The Merck Manuals: The Merck Manual for Patients and Caregivers. http://www.merckmanuals.com/home/older_peoples_health_issues/the_aging_body/disorders_of_accelerated_aging.html. Accessed Jan. 29, 2014.
- When your child is diagnosed with chronic illness: How to cope. American Psychological Association. https://www.apa.org/helpcenter/chronic-illness-child.aspx. Accessed Jan. 29, 2014.
- Coping with chronic illness. American Academy of Pediatrics. http://www.healthychildren.org/English/health-issues/conditions/chronic/pages/Coping-With-Chronic-Illness.aspx. Accessed Jan. 29, 2014.
- Progeria. National Institutes of Health. http://report.nih.gov/NIHfactsheets/ViewFactSheet.aspx?csid=59&key=P#P. Accessed Jan. 29, 2014.
- Gordon LB, et al. Hutchinson-Gilford progeria syndrome. GeneReviews (Internet). http://www.ncbi.nlm.nih.gov/books/NBK1121/. Accessed Jan. 29, 2014.
- Coppede F. Premature aging syndrome. Advances in Experimental Medicine and Biology. 2012;724:317.
- Kirmani S (expert opinion). Mayo Clinic, Rochester, Minn. Feb. 19, 2014.
- Johnson JN (expert opinion). Mayo Clinic, Rochester, Minn. Feb. 23, 2014.
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