Usually within the first year of life, growth of a child with progeria slows markedly so that height and weight fall below average for his or her age. Motor development and intelligence remain normal.

Signs and symptoms of this progressive disorder include:

  • Slowed growth, with below-average height and weight
  • A narrowed face and beaked nose
  • Hair loss (alopecia), including eyelashes and eyebrows
  • Hardening and tightening of skin on trunk and extremities (scleroderma)
  • Head disproportionately large for face
  • Thin lips
  • Visible veins
  • Prominent eyes
  • Small lower jaw (micrognathia)
  • High-pitched voice
  • Delayed and abnormal tooth formation
  • Diminished body fat and muscle
  • Stiff joints
  • Hip dislocation
  • Insulin resistance
  • Irregular heartbeat

When to see a doctor

Call for an appointment with your doctor if your child does not appear to be growing or developing normally, including problems with hair loss, skin changes or slowed growth.

Apr. 23, 2011