Children with progeria usually develop severe hardening of the arteries. This is a condition in which the walls of their arteries — blood vessels that carry nutrients and oxygen from the heart to the rest of the body — stiffen and thicken, often restricting blood flow.
Most children with progeria die of complications related to atherosclerosis, including:
- Problems with blood vessels that supply the heart (cardiovascular problems), resulting in heart attack and congestive heart failure
- Problems with blood vessels that supply the brain (cerebrovascular problems), resulting in stroke
Other health problems frequently associated with aging — such as arthritis, nearsightedness and increased cancer risk — do not develop as part of the course of progeria.
May 03, 2014
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