Factors that may increase the risk of primary sclerosing cholangitis include:

  • Your age. Primary sclerosing cholangitis can occur at any age, but it's most commonly diagnosed in people ages 25 to 45.
  • Your sex. Primary sclerosing cholangitis occurs more often in men than it does in women.
  • Inflammatory bowel disease. The great majority of people with primary sclerosing cholangitis also have inflammatory bowel disease, which includes ulcerative colitis and Crohn's disease. Still, primary sclerosing cholangitis is rare among people with inflammatory bowel disease, and most won't develop primary sclerosing cholangitis. It's not clear why these diseases occur together. If you've been diagnosed with primary sclerosing cholangitis, your doctor may recommend testing for inflammatory bowel disease, even if you have no signs or symptoms.
Apr. 09, 2011

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