Primary progressive aphasia is caused by a shrinking (atrophy) of the frontal and temporal lobes in the brain, primarily on the left side of the brain. Primary progressive aphasia affects the language center in your brain. Scar tissue and abnormal proteins also may be present, and brain activity is often reduced.
Sept. 15, 2015
- Ropper AH, et al. Adams & Victor's Principles of Neurology. 9th ed. New York, N.Y.: The McGraw-Hill Companies; 2009. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=54. Accessed Oct. 12, 2012.
- Gorno-Tempini ML, et al. Classification of primary progressive aphasia and its variants. Neurology. 2011;76:1006.
- Harciarek M, et al. Primary progressive aphasias and their contribution to the contemporary knowledge about the brain-language relationship. Neuropsychology Review. 2011;21:271.
- NINDS frontotemporal dementia information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/picks/picks.htm. Accessed Oct. 12, 2012.
- Rogalski E, et al. Increased frequency of learning disability in patients with primary progressive aphasia and their first-degree relatives. Archives of Neurology. 2008;65:244.
- Approach to the patient with aphasia. http://www.uptodate.com/index. Accessed Oct. 12, 2012.
- Neurological diagnostic tests and procedures. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/misc/diagnostic_tests.htm. Accessed Oct. 24, 2012.
- Aphasia. National Institute on Deafness and Other Communication Disorders. http://www.nidcd.nih.gov/health/voice/pages/aphasia.aspx. Accessed Oct. 29, 2012.
- Communicating with people who have aphasia. The National Aphasia Association. http://www.aphasia.org/Aphasia%20Facts/communicating_with_people_who_have_aphasia.html. Accessed Oct. 29, 2012.
- Caring for a person with a frontotemporal disorder. National Institute on Aging. http://www.nia.nih.gov/alzheimers/publication/frontotemporal-disorders-information-patients-families-and-caregivers/caring. Accessed Oct. 31, 2012.
- Treatment and management. National Institute on Aging. http://www.nia.nih.gov/alzheimers/publication/frontotemporal-disorders-information-patients-families-and-caregivers-0. Accessed Oct. 31, 2012.
- Boeve BF (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 20, 2012.
- Duffy JR (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 26, 2012.