SymptomsBy Mayo Clinic Staff
Although some people with primary biliary cirrhosis remain symptom-free for years after they're diagnosed, others experience a number of signs and symptoms.
Common early symptoms include:
- Itchy skin
- Dry eyes and mouth
Later signs and symptoms may include:
May 16, 2017
- Pain in the upper right portion of the abdomen
- Bone, muscle or joint (musculoskeletal) pain
- Yellowing of the skin and eyes (jaundice)
- Darkening of the skin that's not related to sun exposure (hyperpigmentation)
- Swollen feet and ankles (edema)
- Buildup of fluid in the abdomen due to liver failure (ascites)
- Fatty deposits on the skin around your eyes, your eyelids, or in the creases in your palms, soles, elbows or knees (xanthomas)
- Weak and brittle bones (osteoporosis), which can lead to fractures
- Elevated cholesterol
- Diarrhea that can be greasy (steatorrhea)
- Underactive thyroid (hypothyroidism)
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