Factors that increase a child's risk of precocious puberty include:
Jan. 02, 2014
- Being a girl. Girls are much more likely to develop precocious puberty.
- Being African-American. Precocious puberty affects African-Americans more often than children of other races.
- Being obese. If your daughter is significantly overweight, she has a higher risk of developing precocious puberty.
- Being exposed to sex hormones. Coming in contact with an estrogen or testosterone cream or ointment, or other substances that contain these hormones (such as an adult's medication or dietary supplements), can increase your child's risk of developing precocious puberty.
- Having other medical conditions. Precocious puberty may be a complication of McCune-Albright syndrome or congenital adrenal hyperplasia — conditions that involve abnormal production of the male hormones (androgens). In rare cases, precocious puberty may also be associated with hypothyroidism.
- Having received radiation therapy of the central nervous system. Radiation treatment for tumors, leukemia or other conditions can increase the risk of precocious puberty.
- Saenger P. Definition, etiology and evaluation of precocious puberty. http://www.uptodate.com/home. Accessed Aug. 26, 2013.
- Precocious puberty. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec19/ch282/ch282h.html. Accessed Aug. 27, 2013.
- Saenger P. Treatment of precocious puberty. http://www.uptodate.com/home. Accessed Aug. 26, 2013.
- Melmed S, et al. Williams Textbook of Endocrinology. 12th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. https://www.clinicalkey.com. Accessed Aug. 26, 2013.
- Burt Solarzano CM, et al. Obesity and pubertal transition in girls and boys. Reproduction. 2010;140:399.
- Tolson KP, et al. The changes they are a-timed: Metabolism, endogenous clocks and the timing of puberty. Frontiers in Endocrinology. 2012;3:1.
- Fuqua JS. Treatment and outcomes of precocious puberty: An update. Journal of Clinical Endocrinology and Metabolism. 2013;98:2198.