Below are current clinical trials.3 studies in Pneumonia
(open studies only).
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This is a Phase IV randomized, double-blinded, placebo-controlled study in 1000 individuals aged 18 years or older, with community acquired pneumonia (CAP) who meet all eligibility criteria in endemic regions. This study is designed to provide data on the effectiveness of early antifungal treatment (Fluconazole, 400 mg/day) for coccidioidomycosis pneumonia (also referred to as Valley Fever (VF) Pneumonia or acute onset valley fever) vs. placebo in subjects with coccidioidomycosis pneumonia. Patients who are prescribed antibacterials by their health care provider for acute CAP will be randomized to receive either placebo or 400 mg/day of fluconazole for 42 days. The primary objective is to assess the clinical response of early empiric antifungal therapy with fluconazole through Day 22 in subjects with coccidioidomycosis pneumonia and are compliant with the study intervention.
The purpose of this study is to identify, recruit, and enroll patients with community-acquired pneumonia (CAP) to collect their blood, sputum, urine, and a nasopharyngeal swab for specimen storage. The study also aims to develop a biomarker assay to detect circulating antigen in patients infected with Coccidioides.
The purpose of this study is to identify potential pathogens in parapneumonic effusions associated with community acquired pneumonia and health care acquired pneumonia.
June 21, 2016
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- File TM. Treatment of community-acquired pneumonia in adults in the outpatient setting. http://www.uptodate.com/home. Accessed April 20, 2016.
- Chang CC, et al. Over-the-counter (OTC) medications to reduce cough as an adjunct to antibiotics for acute pneumonia in children and adults. Cochrane Database of Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD006088.pub4/full. Accessed April 20, 2016.
- Mycoplasma pneumoniae infection. Centers for Disease Control and Prevention. http://www.cdc.gov/pneumonia/atypical/mycoplasma/. Accessed April 20, 2016.
- Barson WJ. Community-acquired pneumonia in children: Clinical features and diagnosis. http://www.uptodate.com/home. Accessed April 20, 2016.
- Olson EJ (expert opinion). Mayo Clinic, Rochester, Minn. May 1, 2016.