Peyronie disease care at Mayo Clinic

  • Your Mayo Clinic care team. Urologists at Mayo Clinic specialize in treating Peyronie disease and treat more than 940 people who have this condition each year.
  • Advanced diagnosis and treatment. Mayo Clinic specialists carefully evaluate your condition and develop a tailored treatment plan that may include medicine, physical therapy or surgery.
  • Nationally recognized expertise. Mayo specialists have expert knowledge about experimental treatments for Peyronie disease. They are skilled at the delicate microsurgery needed to restore regular shape and function of the penis.

Breaking the curve: Understanding Peyronie disease and solutions at Mayo Clinic

Watch as a Mayo Clinic expert explains Peyronie disease and what treatments are available at Mayo Clinic.

Matthew Ziegelmann, M.D., Urologist: If you're out with your buddies and you've got six or ten guys around the table, probably someone else at that table is suffering from sexual dysfunction like Peyronie's disease, and you're just not talking about it.

I focus on men's health and specifically my clinical interest is in Peyronie's disease and erectile dysfunction. Peyronie's disease is actually a lot more common than you might imagine. Scar tissue forms on the erectile bodies of the penis and creates specific constellation of symptoms, and that can be pain with erections, curvature of the penis, indentation or loss of girth with an erection. Here we offer essentially the gamut of evidence-based therapies for Peyronie's Disease. We have high volumes of all of those treatments, whether that's non-surgical therapies, whether that's injection therapies. And ultimately a big part of my practice is offering surgical management for Peyronie's Disease.

I love the idea of being able to be involved in what many people consider an intimate and private portion of their life, and provide patients with comfort and understanding, but also meaningful treatments that really do impact patients quality of life.

J. Marc Vezina, patient: The level of a relationship do you have to have with a doctor in order to discuss. This is probably the reason why most men don't get this done or don't seek treatment. I did my homework. My criterion where I wanted an academic medical center, I wanted the place that had volume, and I want a place that's considered a thought leader in this area.

Dr. Ziegelmann: Peyronie's disease is not likely to get any better without some type of intervention. So if somebody is bothered by their symptoms and they've had this condition for a long time and they've been reticent to come in and get evaluated, that's okay. We haven't missed some window of opportunity.

When Marc came to see me, he came in the context of having started his care elsewhere and that included injections.

Marc: I did a months of injections, no result. So I was very frustrated and I knew I wanted to have a surgery, and I knew I wanted to have a world-class facility do it.

Dr. Ziegelmann: He estimated about 45 to 60 degrees of curvature. When we ultimately brought him to the operating room and performed his surgery, it was actually even more severe. It was about 70 degrees of curvature, which is quite substantial. The more experience you have in operative management of any condition, the better. There's lots of literature that suggests that higher volumes are associated with better outcomes with surgery. When it comes to Peyronie's disease, I think this is absolutely true because of the complex nature of the anatomy that's involved in the complex approaches that we use to treat Peyronie's disease. And so you want someone who has a lot of experience, who really has made this a big part of their practice.

Marc: I felt great after the procedure, had no pain and I was on cloud nine.

Dr. Ziegelmann: I love the mix of medical and surgical practice and procedural practice that we offer at Mayo Clinic. I'm enthusiastic about the types of problems that men come in with and how we have actual, real solutions for them.

One of the things I love about working at Mayo is that I have the opportunity to really subspecialize and focus my practice so I get to really understand this disease process in a very specific way. You are their mission when you come here.

Marc:If I could send a message to any man out there that has this problem, get on a plane and come here right away and find out what your options are.

Dr. Ziegelmann: At Mayo Clinic, we have the ability to see a large number of patients with a specific type of problem, to offer the ability to diagnose that problem, to offer the ability to counsel as effectively as possible, and ultimately to offer a spectrum of appropriate treatments with high volume so that we have the experience to get you the best outcomes possible. Again, I really think that's a unique aspect of our practice here at Mayo Clinic.

Expertise and rankings

Expertise and experience

Mayo Clinic specialists have extensive experience and expertise in caring for people with Peyronie disease, treating more than 940 people each year.

Mayo Clinic in Minnesota ranks among the best hospitals for urology in the U.S. News & World Report Best Hospitals rankings.

Peyronie disease care at Mayo Clinic

Learn more from urologist Matthew J. Ziegelmann, M.D.

Locations, travel and lodging

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Costs and insurance

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

More information about billing and insurance:

Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

Mayo Clinic Men's Health Center

For more information on Peyronie disease care at Mayo Clinic, visit the Mayo Clinic Men's Health Center.

There you can learn more about a variety of conditions affecting men's health. You have the opportunity to complete questionnaires tailored to specific conditions and procedures. Mayo Clinic's men's health experts provide valuable feedback and can help you schedule an appointment for care at Mayo Clinic, if that's determined to be your next step.

Plus, you have access to dozens of informative videos made by Mayo Clinic's team of men's health experts that can help you better understand your condition and treatment options.

Peyronie disease care at Mayo Clinic

Our caring team of Mayo Clinic experts can help you with your health concerns. Visit Mayo Clinic Men's Health to get started.

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March 27, 2024