In most cases, Paget's disease of bone progresses slowly. The disease can be managed effectively in nearly all people. Possible complications include:

  • Fractures. Bones affected by Paget's disease break more easily. Extra blood vessels are created in these deformed bones, so they bleed more during repair surgeries.
  • Osteoarthritis. Misshapen bones can increase the amount of stress on nearby joints, which can cause osteoarthritis.
  • Heart failure. Unusually extensive Paget's disease may force your heart to work harder to pump blood to the affected areas of your body. In people with pre-existing heart disease, this increased workload can lead to heart failure.
  • Bone cancer. Bone cancer occurs in less than 1 percent of people with Paget's disease.
Feb. 13, 2013

You Are ... The Campaign for Mayo Clinic

Mayo Clinic is a not-for-profit organization. Make a difference today.