About 1 to 2 percent of women undergoing ovarian stimulation develop a severe form of ovarian hyperstimulation syndrome. Severe OHSS can be life-threatening. Complications may include:

  • Fluid collection in the abdomen and sometimes the chest
  • Electrolyte disturbances (sodium, potassium, others)
  • Blood clots in large vessels, usually in the legs
  • Kidney failure
  • Twisting of an ovary
  • Rupture of a cyst in an ovary, which can lead to serious bleeding
  • Breathing problems
  • Pregnancy loss from miscarriage or termination because of complications
  • Rarely, death
Feb. 14, 2014