Aug. 13, 2014
Below are current clinical trials.1 studies in Ovarian cysts
(open studies only).
Filter this list of studies by location, status and more.
MV-NIS Infected Mesenchymal Stem Cells in Treating Patients With Recurrent Ovarian Cancer
Study type: Interventional What is this?
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study phase: I/II What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.
About this study
This phase I/II trial studies the side effects and best dose of oncolytic measles virus encoding thyroidal sodium iodide symporter (MV-NIS) infected mesenchymal stem cells and to see how well it works in treating patients with recurrent ovarian cancer. Mesenchymal stem cells may be able to carry tumor-killing substances directly to ovarian cancer cells.
Participating Mayo Clinic locations
Study statuses change often. Please contact us for help.
Print study details
- Rochester, Minnesota: 12-007859
NCT ID: NCT02068794
Sponsor Protocol Number: MC1266
- Ovarian cysts. The American College of Obstetricians and Gynecologists. http://www.acog.org/~/media/For%20Patients/faq075.pdf?dmc=1&ts=20140523T1226073428. Accessed May 23, 2014.
- Lentz GM, et al. Comprehensive Gynecology. 6th ed. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.clinicalkey.com. Accessed May 24, 2014.
- Ferri FF. Ferri's Clinical Advisor 2014: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2014. https://www.clinicalkey.com. Accessed May 24, 2014.
- Liu JH, et al. Management of the adnexal mass. Obstetrics & Gynecology. 2011;117:1413.
- Muto MG. Management of the adnexal mass. http://www.uptodate.com/home. Accessed May 23, 2014.
- Hoffman MS. Differential diagnosis of the adnexal mass. http://www.uptodate.com/home. Accessed May 28, 2014.
- Muto MG. Approach to the patient with an adnexal mass. http://www.uptodate.com/home. Accessed May 23, 2014.
- Ovarian cysts fact sheet. Office on Women's Health, U.S. Department of Health and Human Services. http://www.womenshealth.gov/publications/our-publications/fact-sheet/ovarian-cysts.html. Accessed May 23, 2014.