Overview

Ovarian cysts are sacs, usually filled with fluid, in an ovary or on its surface. Females have two ovaries. One ovary is located on each side of the uterus.

Each ovary is about the size and shape of an almond. Eggs develop and mature in the ovaries. Eggs are released in monthly cycles during the childbearing years.

Ovarian cysts are common. Most of the time, you have little or no discomfort, and the cysts are harmless. Most cysts go away without treatment within a few months.

But sometimes ovarian cysts can become twisted or burst open (rupture). This can cause serious symptoms. To protect your health, get regular pelvic exams and know the symptoms that can signal what might be a serious problem.

Symptoms

Most ovarian cysts cause no symptoms and go away on their own. But a large ovarian cyst can cause:

  • Pelvic pain that may come and go. You may feel a dull ache or a sharp pain in the area below your bellybutton toward one side.
  • Fullness, pressure or heaviness in your belly (abdomen).
  • Bloating.

When to see a doctor

Get immediate medical help if you have:

  • Sudden, severe abdominal or pelvic pain.
  • Pain with fever or vomiting.
  • Signs of shock. These include cold, clammy skin; rapid breathing; and lightheadedness or weakness.

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Causes

Most ovarian cysts form as a result of your menstrual cycle. These are called functional cysts. Other types of cysts are much less common.

Functional cysts

Your ovaries grow small cysts called follicles each month. Follicles produce the hormones estrogen and progesterone and break open to release an egg when you ovulate.

A monthly follicle that keeps growing is known as a functional cyst. There are two types of functional cysts:

  • Follicular cyst. About halfway through your menstrual cycle, an egg bursts out of its follicle. The egg then travels down a fallopian tube. A follicular cyst begins when the follicle doesn't rupture. It doesn't release its egg and continues to grow.
  • Corpus luteum cyst. After a follicle releases its egg, it shrinks and begins producing estrogen and progesterone. These hormones are needed for conception. The follicle is now called the corpus luteum. Sometimes, the opening where the egg came from gets blocked. Fluid builds up inside the corpus luteum, causing a cyst.

Functional cysts are usually harmless. They rarely cause pain and often disappear on their own within 2 to 3 menstrual cycles.

Other cysts

There are other types of cysts that are not related to menstrual cycles:

  • Dermoid cyst. Also called a teratoma, this cyst forms from reproductive cells that make eggs in the ovary (germ cells). The cyst can contain tissue, such as hair, skin or teeth. This type of cyst is rarely cancer.
  • Cystadenoma. This type of cyst develops from cells on the surface of an ovary. The cyst might be filled with a watery or mucous material. A cystadenoma can grow very large.
  • Endometrioma. Endometriosis is a condition that causes cells similar to those that line the inside of the uterus to grow outside the uterus. Some of the tissue can attach to the ovary and form a cyst. This is called an endometrioma.

Dermoid cysts and cystadenomas can become large and move the ovary out of position. This increases the chance of painful twisting of the ovary, called ovarian torsion. Ovarian torsion may reduce or stop blood flow to the ovary.

Video: Ovulation

Ovulation is the release of an egg from one of the ovaries. It often happens about midway through the menstrual cycle, although the exact timing may vary.

In preparation for ovulation, the lining of the uterus, or endometrium, thickens. The pituitary gland in the brain stimulates one of the ovaries to release an egg. The wall of the ovarian follicle ruptures at the surface of the ovary. The egg is released.

Finger-like structures called fimbriae sweep the egg into the neighboring fallopian tube. The egg travels through the fallopian tube, propelled in part by contractions in the fallopian tube walls. Here in the fallopian tube, the egg may be fertilized by a sperm.

If the egg is fertilized, the egg and sperm unite to form a one-celled entity called a zygote. As the zygote travels down the fallopian tube toward the uterus, it begins dividing rapidly to form a cluster of cells called a blastocyst, which resembles a tiny raspberry. When the blastocyst reaches the uterus, it implants in the lining of the uterus and pregnancy begins.

If the egg isn't fertilized, it's simply reabsorbed by the body — perhaps before it even reaches the uterus. About two weeks later, the lining of the uterus sheds through the vagina. This is known as menstruation.

Risk factors

The risk of having an ovarian cyst is higher with:

  • Hormonal problems. These include taking a fertility drug that causes you to ovulate, for example clomiphene or letrozole (Femara).
  • Pregnancy. Sometimes, the follicle that forms when you ovulate stays on your ovary throughout pregnancy. It can sometimes grow larger.
  • Endometriosis. Some of the tissue can attach to your ovary and form a cyst.
  • Severe pelvic infection. If the infection spreads to the ovaries, it can cause cysts.
  • Previous ovarian cysts. If you've had one ovarian cyst, you're likely to develop more.

Complications

They don't happen often, but complications can occur with ovarian cysts. These include:

  • Ovarian torsion. Cysts that become large can cause the ovary to move. This increases the chance of painful twisting of the ovary (ovarian torsion). If this happens, you might have sudden, severe pelvic pain and nausea and vomiting. Ovarian torsion can also reduce or stop blood flow to the ovary.
  • Cyst rupture. A cyst that bursts open (ruptures) can cause severe pain and bleeding inside the pelvis. The larger the cyst, the greater the risk of rupture. Vigorous activity that affects the pelvis, such as vaginal sex, also increases the risk of rupture.

Prevention

There's no way to prevent most ovarian cysts. But, regular pelvic exams help ensure that changes in your ovaries are diagnosed as early as possible. Be alert to changes in your monthly cycle. Make a note of unusual menstrual symptoms, especially ones that go on for more than a few cycles. Talk to your health care provider about changes that concern you.

July 28, 2023
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