CausesBy Mayo Clinic Staff
Although there are genetic, behavioral and hormonal influences on body weight, obesity occurs when you take in more calories than you burn through exercise and normal daily activities. Your body stores these excess calories as fat.
Obesity can sometimes be traced to a medical cause, such as Prader-Willi syndrome, Cushing's syndrome, and other diseases and conditions. However, these disorders are rare and, in general, the principal causes of obesity are:
June 10, 2015
- Inactivity. If you're not very active, you don't burn as many calories. With a sedentary lifestyle, you can easily take in more calories every day than you use through exercise and normal daily activities.
- Unhealthy diet and eating habits. Weight gain is inevitable if you regularly eat more calories than you burn. And most Americans' diets are too high in calories and are full of fast food and high-calorie beverages.
- AskMayoExpert. Obesity. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2014.
- Defining overweight and obesity. Centers for Disease Control and Prevention. http://www.cdc.gov/obesity/adult/defining.html. Accessed March 9, 2015.
- Jensen MD, et al. 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults. Journal of the American College of Cardiology. 2014;63(25 Pt B):2985.
- Bray GA. Pathogenesis of obesity. http://www.uptodate.com/home. Accessed March 9, 2015.
- What are overweight and obesity? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/obe#. Accessed March 9, 2015.
- Bray GA. Obesity in adults: Etiology and natural history. http://www.uptodate.com/home. Accessed March 9, 2015.
- Bray GA. Obesity in adults: Health hazards. http://www.uptodate.com/home. Accessed March 9, 2015.
- Understanding adult overweight and obesity. National Institute of Diabetes and Digestive and Kidney Diseases. http://win.niddk.nih.gov/publications/understanding.htm. Accessed March 9, 2015.
- Papadakis MA, et al. Nutritional disorders. In: Current Medical Diagnosis & Treatment 2014. 53rd ed. New York, N.Y.: The McGraw-Hill Companies; 2014. http://www.accessmedicine.com. Accessed March 9, 2015
- Sacks F, et al. Comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates. New England Journal of Medicine. 2009;360:859.
- Moyer VA, et al. Screening for and management of obesity in adults: U.S. Preventive Services Task Force recommendation statement. Annals of Internal Medicine. 2012;157:373.
- Bray GA. Obesity in adults: Drug therapy. http://www.uptodate.com/home. Accessed March 9, 2015.
- Greenberger NJ, et al. Treatment of obesity: The impact of bariatric surgery. In: Current Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy. 2nd ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com. Accessed March 9, 2015.
- Nelson DW, et al. Analysis of obesity-related outcomes and bariatric failure rates with the duodenal switch vs. gastric bypass for morbid obesity. Archives of Surgery. 2012;147:847.
- Weight control and complementary health practices: What the science says. National Center for Complementary and Integrative Health. http://nccih.nih.gov/health/providers/digest/weightloss-science. Accessed March 9, 2015.
- FDA approves first of kind device to treat obesity. U.S. Food and Drug Administration. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm430223.htm. Accessed Jan. 27, 2015.
- Pharmacological management of obesity: An Endocrine Society clinical practice guideline. Journal of Clinical Endocrinology & Metabolism. 2015;100:342.
- Kim SB. Surgical management of severe obesity. http://www.uptodate.com/home. Accessed March 12, 2015.
- Ikramuddin S, et al. Effect of reversible intermittent intra-abdominal vagal nerve blockade on morbid obesity: The ReCharge randomized clinical trial. JAMA. 2014;312:915.
- Hensrud DD, et al., eds. The Mayo Clinic Diet. Intercourse, Pa.: Good Books; 2013.