Below are current clinical trials.3 studies in Nicotine dependence
(open studies only).
Filter this list of studies by location, status and more.
In the southwest region of Alaska where the project takes place, 79% of Alaska Native women smoke cigarettes or use smokeless tobacco (ST) during pregnancy. In addition, pregnancy appears to be a high risk period for initiation of tobacco use, primarily ST, among women reporting no use of tobacco 3 months before pregnancy. Intervention efforts targeting the entire community, not only pregnant women, to address social norms about tobacco use may be effective. Thus, the investigators will evaluate the efficacy of a novel, multi-component, theory-based intervention for reducing tobacco use during pregnancy, incorporating both individually targeted and community level components delivered by female elders "Native Sisters." The intervention builds on effective community and individual-based approaches for tobacco cessation and lay health advisor approaches for cancer prevention among Native American women. As part of the intervention, a social marketing campaign including digital stories and other small media will be developed with community feedback. Individually targeted components will be six 30-40 minute telephone or home-based peer counseling sessions with pregnant women.
La Crosse, Wis., Mankato, Minn., Rochester, Minn.
This randomized phase III trial studies how well smoking cessation intervention works in reducing surgical complications in patients with newly diagnosed lung cancer who smoke cigarettes. This study will use two smoking cessation interventions: Varenicline (a drug that reduces the craving and withdrawal symptoms that occur with abstinence from nicotine) with behavioral interventions (consisting of a brief clinician-delivered intervention and tobacco quitline [tobacco cessation service available through a toll-free telephone number] follow-up) with placebo (a pill with no active medication) along with the same behavioral interventions. It is not yet known whether smoking cessation intervention prior to surgery is effective in reducing surgical complications for these patients.
This pilot study is being done to adapt an effective 1 session phone coaching intervention for nonsmoking support persons to a low income population. This study will also pilot new intervention components including text messaging and health incentives. The goal of the intervention is for support persons to prompt their smoker to use quitline services. To see if these methods are effective, smokers in this study will be asked to complete assessments about their quit attempts and smoking status. The study will also evaluate if the smokers use quitline services or not. The preliminary findings will be used to provide data for an R01 NIH grant submission.
May 03, 2016
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- Bupropion. Facts & comparisons eAnswers. http://www.wolterskluwercdi.com/facts-comparisons-online/. Accessed March 31, 2016.
- Varenicline. Facts & comparisons eAnswers. http://www.wolterskluwercdi.com/facts-comparisons-online/. Accessed March 31, 2016.
- Nortriptyline. Facts & comparisons eAnswers. http://www.wolterskluwercdi.com/facts-comparisons-online/. Accessed March 31, 2016.
- Complementary health approaches for smoking cessation: What the science says. National Center for Complementary and Integrative Health. https://nccih.nih.gov/health/providers/digest/smoking-science. Accessed April 1, 2016.
- Pisinger C, et al. A systematic review of health effects of electronic cigarettes. Preventive Medicine. 2014;69:248.
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- Smokeless tobacco and cancer. National Cancer Institute. http://www.cancer.gov/about-cancer/causes-prevention/risk/tobacco/smokeless-fact-sheet. Accessed April 5, 2016.
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- Hookahs. Centers for Disease Control and Prevention. http://www.cdc.gov/tobacco/data_statistics/fact_sheets/tobacco_industry/hookahs/. Accessed April 5, 2016.
- Cigars. Centers for Disease Control and Prevention. http://www.cdc.gov/tobacco/data_statistics/fact_sheets/tobacco_industry/cigars/index.htm. Accessed April 5, 2016.
- Bidis and kreteks. Centers for Disease Control and Prevention. http://www.cdc.gov/tobacco/data_statistics/fact_sheets/tobacco_industry/bidis_kreteks/index.htm. Accessed April 5, 2016.
- Kotz D, et al. Prospective cohort study of the effectiveness of smoking cessation treatments used in the 'real world.' Mayo Clinic Proceedings. 2014;89:1360.