DefinitionBy Mayo Clinic Staff
Myelodysplastic syndromes are a group of disorders caused by poorly formed or dysfunctional blood cells. Myelodysplastic syndromes occur when something goes wrong in your bone marrow — the spongy material inside your bones where blood cells are made.
Treatment for myelodysplastic syndromes usually focuses on reducing or preventing complications of the disease and its treatments. In certain cases, myelodysplastic syndromes are treated with a bone marrow transplant.
Nov. 11, 2014
- Myelodysplastic syndromes. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed Sept. 24, 2014.
- Myelodysplastic syndromes treatment (PDQ). National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/myelodysplastic/Patient. Accessed Sept. 24, 2014.
- Vardiman JW, et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: Rationale and important changes. Blood. 2009;114:937.
- Niederhuber JE, et al. Abeloff's Clinical Oncology. 5th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2014. http://www.clinicalkey.com. Accessed Sept. 24, 2014.
- Hoffman R, et al. Hematology: Basic Principles and Practice. 6th ed. Philadelphia, Pa.: Saunders Elsevier; 2013. http://www.clinicalkey.com. Accessed Sept. 24, 2014.
- Cook AJ. Decision Support System. Mayo Clinic, Rochester, Minn. July 7, 2014.
- MDS Centers of Excellence. MDS Foundation. http://www.mds-foundation.org/mds-centers-of-excellence/. Accessed Sept. 25, 2014.