Moyamoya disease is a rare blood vessel (vascular) disorder in which a ring of blood vessels at the base of your brain (the circle of Willis) and the uppermost (distal) segments of the arteries supplying the brain progressively narrow, causing blood flow to your brain to become reduced.
The condition may cause a ministroke (transient ischemic attack), stroke or other symptoms.
Moyamoya disease mainly affects children, but adults may have the condition. Moyamoya disease usually occurs in people from Japan and other Asian countries, but people in North America, Europe and other areas also have moyamoya disease.
April 26, 2014
Watch Mayo Clinic neurosurgeon Fredric B. Meyer, M.D., discuss moyamoya disease on YouTube.
- NINDS moyamoya disease information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/moyamoya/moyamoya.htm. Accessed Oct. 28, 2013.
- Suwanwela NC. Moyamoya disease: Etiology, clinical features, and diagnosis. http://www.uptodate.com/home. Accessed Oct. 28, 2013.
- Weinberg DG, et al. Moyamoya disease: A review of histopathology, biochemistry, and genetics. Neurosurgical Focus. 2011;30:E20.
- Riggin EA. Decision Support System. Mayo Clinic, Rochester, Minn. Oct. 8, 2013.
- Neurological diagnostic tests and procedures. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/misc/diagnostic_tests.htm. Accessed Oct. 28, 2013.
- Suwanwela NC. Moyamoya disease: Treatment and prognosis. http://www.uptodate.com/home. Accessed Oct. 28, 2013.
- Baaj AA, et al. Surgical management of moyamoya disease: A review. Neurosurgical focus. 2009;26:E7.
- Pandey P, et al. Neurosurgical advances in the treatment of moyamoya disease. Stroke. 2011;42:3304.
- Brown RD (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 6, 2013.
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