DefinitionBy Mayo Clinic Staff
Morphea (mor-FEE-uh) is a rare skin condition that causes painless, discolored patches on your skin.
Typically, the skin changes appear on the abdomen, chest or back. But they might also appear on your face, arms or legs. Morphea tends to affect only the outermost layers of your skin. But some forms of the condition also restrict movement in the joints.
Morphea usually subsides on its own over time, though recurrences are common. In the meantime, medications and therapies are available to help treat the skin discoloration and other effects.
Sept. 29, 2015
- AskMayoExpert. Morphea. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2014.
- Goldsmith LA, et al., eds. Morphea. In: Fitzpatrick's Dermatology in General Medicine. 8th ed. New York, N.Y.: The McGraw-Hill Companies; 2012.
- Ravelli NF, et al. Interventions for morphea. Cochrane Database of Systematic Reviews. http://ovidsp.tx.ovid.com/sp-3.16.0b/ovidweb.cgi. Accessed Aug. 6, 2015.
- Tolkachjov SN, et al. Progressive hemifacial atrophy: A review. Orphanet Journal of Rare Diseases. 2015;10:39.
- Sartori-Valinoitt JC, et al. Updates on morphea: Role of vascular injury and advances in treatment. Autoimmune Diseases. 2013;2013:467808.
- Para-aminobenzoic acid (PABA). Natural Medicines Comprehensive Database. http://naturaldatabase.therapeuticresearch.com/nd/PrintVersion.aspx?cs=MAYO&s=ND. Accessed Aug. 6, 2015.
- Valanclene G, et al. Pathogenesis and treatment modalities of localized scleroderma. Medicina (Kaunas). 2010;46:649.