Para-aminobenzoic acid (PABA) is an oral medication that has been used to treat morphea. But it hasn't been proved to reduce skin symptoms in clinical trials. If you're interested in trying PABA, discuss its proper use with your doctor.
Sept. 29, 2015
- AskMayoExpert. Morphea. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2014.
- Goldsmith LA, et al., eds. Morphea. In: Fitzpatrick's Dermatology in General Medicine. 8th ed. New York, N.Y.: The McGraw-Hill Companies; 2012.
- Ravelli NF, et al. Interventions for morphea. Cochrane Database of Systematic Reviews. http://ovidsp.tx.ovid.com/sp-3.16.0b/ovidweb.cgi. Accessed Aug. 6, 2015.
- Tolkachjov SN, et al. Progressive hemifacial atrophy: A review. Orphanet Journal of Rare Diseases. 2015;10:39.
- Sartori-Valinoitt JC, et al. Updates on morphea: Role of vascular injury and advances in treatment. Autoimmune Diseases. 2013;2013:467808.
- Para-aminobenzoic acid (PABA). Natural Medicines Comprehensive Database. http://naturaldatabase.therapeuticresearch.com/nd/PrintVersion.aspx?cs=MAYO&s=ND. Accessed Aug. 6, 2015.
- Valanclene G, et al. Pathogenesis and treatment modalities of localized scleroderma. Medicina (Kaunas). 2010;46:649.