In mitral valve disease, the mitral valve, which is located between your left heart chambers (left atrium and left ventricle), doesn't work properly.

Types of mitral valve disease include:

Mitral valve regurgitation

In this condition, the flaps (leaflets) of the mitral valve don't close tightly, causing blood to leak backward into the left atrium of your heart. If not treated, it can result in heart muscle damage.

This condition is commonly caused by mitral valve prolapse, in which the leaflets bulge back into the left atrium as your heart contracts.

Mitral valve stenosis

In this condition, the flaps of the mitral valve become thick or stiff, and they may fuse together. This results in a narrowed valve opening and reduced blood flow from the left atrium to the left ventricle.

Treatment for mitral valve disease depends on the severity of your condition and whether your condition is becoming worse. Your doctor may eventually recommend that you have surgery to repair or replace your mitral valve.

Mitral valve disease care at Mayo Clinic

March 03, 2017
  1. Mitral regurgitation. Merck Manual Professional Version. http://www.merckmanuals.com/professional/cardiovascular-disorders/valvular-disorders/mitral-regurgitation. Accessed Sept. 23, 2016.
  2. Mitral stenosis. Merck Manual Professional Version. http://www.merckmanuals.com/professional/cardiovascular-disorders/valvular-disorders/mitral-stenosis. Accessed Sept. 22, 2016.
  3. What is heart valve disease? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/hvd. Accessed Sept. 20, 2016.
  4. Bonow RO, et al., eds. Valvular heart disease. In: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 10th ed. Philadelphia, Pa.: Saunders Elsevier; 2015. http://www.clinicalkey.com. Accessed Aug. 16, 2016.
  5. Getting support. American Heart Association. http://www.heart.org/HEARTORG/Caregiver/ReachOut/GettingSupport/Getting-Support_UCM_301847_Article.jsp#.WCn5QdgzXIU. Accessed Nov. 4, 2016.
  6. How can I make my lifestyle healthier? American Heart Association. http://www.heart.org/HEARTORG/Conditions/More/ToolsForYourHeartHealth/Answers-by-Heart-Fact-Sheets-Lifestyle-and-Risk-Reduction_UCM_300611_Article.jsp#.WC9socnFjVY. Accessed Nov. 18, 2016.
  7. Nishimura RA, et al. Mitral valve disease — Current management and future challenges. Lancet. 2016;387:1324.
  8. Ruiz CE, et al. Transcatheter therapies for the treatment of valvular and paravalvular regurgitation in acquired and congenital valvular heart disease. Journal of the American College of Cardiology. 2015;66:169.
  9. Nishimura RA, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. The Journal of Thoracic and Cardiovascular Surgery. 2014;148:e1.
  10. AskMayoExpert. Mitral regurgitation. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2016.
  11. Riggin ER. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Aug. 12, 2016.
  12. Taggarse AK, et al. How has robotic repair changed the landscape of mitral valve surgery? Annals of Cardiothoracic Surgery. 2015;4:358.
  13. Daniels BK. Echo Information Management System. Mayo Clinic, Rochester, Minn. Oct 18, 2016.