Research

Having identified the condition, Mayo Clinic researchers continue to study MGUS to better understand it and to improve treatment options. Specific efforts involve determining risk factors for developing the condition, how these risk factors might influence treatment, and how to prevent progression of MGUS to blood cancers and other conditions.

Doctors and scientists in the Hematologic Malignancies Program of the Mayo Clinic Cancer Center are working on improving the diagnosis and treatment of myeloma and other blood disorders.

Publications

See a list of publications by Mayo Clinic doctors on monoclonal gammopathy of undetermined significance (MGUS) on PubMed, a service of the National Library of Medicine.

April 27, 2016
References
  1. Rajkumar SV. Diagnosis of monoclonal gammopathy of undetermined significance. http://www.uptodate.com/home. Accessed Feb. 17, 2016.
  2. Rajkumar SV. Clinical course and management of monoclonal gammopathy of undetermined significance. http://www.uptodate.com/home. Accessed Feb. 17, 2016.
  3. Ferri FF. Monoclonal gammopathy of undetermined significance (MGUS). In: Ferri's Clinical Advisor 2016. Philadelphia, Pa.: Mosby Elsevier; 2016. https://www.clinicalkey.com. Accessed Feb. 17, 2016.
  4. Glavey SV, et al. Monoclonal gammopathy: The good, the bad and the ugly. Blood Reviews. In press. http://dx.doi.org/10.1016/j.blre.2015.12.001. Accessed Feb. 18, 2016.
  5. Goldman L, et al., eds. Plasma cell disorders. In: Goldman-Cecil Medicine. 25th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. http://www.clinicalkey.com. Accessed Feb. 11, 2016.
  6. AskMayoExpert. Monoclonal gammopathy of undetermined significance (MGUS) prevalence. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2015.
  7. Kyle RA, et al. Monoclonal gammopathy of undetermined significance and smoldering multiple myeloma. Hematology/Oncology Clinics of North America. 2014;28:775.
  8. Sethi S, et al. Spectrum of manifestations of monoclonal gammopathy-associated renal syndromes. Current Opinion in Nephrology and Hypertension. 2016;25:127.
  9. AskMayoExpert. Monoclonal gammopathy of undetermined significance (MGUS). Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2014.
  10. Riggin EA. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Jan. 13, 2016.