Factors that increase your risk of monoclonal gammopathy of undetermined significance include:

  • Your age. The risk of monoclonal gammopathy of undetermined significance increases as you get older. The highest incidence is among adults age 85 and older.
  • Your race. Blacks are more likely to experience this condition than are whites.
  • Your sex. Monoclonal gammopathy of undetermined significance is more common in men than it is in women.
  • A family history. If other people in your family have monoclonal gammopathy of undetermined significance, your risk of developing the disorder may be higher.
May. 17, 2013