Treatments and drugs

By Mayo Clinic Staff

Treatment for meralgia paresthetica focuses on relieving compression of the nerve.

Conservative measures

Conservative measures are effective for most people, with pain usually going away within a few months. They include:

  • Wearing looser clothing
  • Losing weight
  • Taking OTC pain relievers such as acetaminophen (Tylenol, others), ibruprofen (Advil, Motrin IB, others) or aspirin


If symptoms persist for more than two months or your pain is severe, treatment may include:

  • Corticosteroid injections. Injections can reduce inflammation and temporarily relieve pain. Possible side effects include joint infection, nerve damage, pain and whitening of skin around the injection site.
  • Tricyclic antidepressants. These medications may relieve your pain. Side effects include drowsiness, dry mouth, constipation and impaired sexual functioning.
  • Gabapentin (Neurontin), phenytoin (Dilantin) or pregabalin (Lyrica). These anti-seizure medications may help lessen your painful symptoms. Side effects include constipation, nausea, dizziness, drowsiness and lightheadedness.


Rarely, surgery to decompress the nerve is considered. This option is only for people with severe and long-lasting symptoms.

March 29, 2014