• High cholesterol. Levels of cholesterol and triglycerides are often high in people with membranous nephropathy, which greatly increases their risk of heart disease.
  • Blood clots. Loss of protein from the blood into the urine (proteinuria) in people with membranous nephropathy includes loss of proteins that help prevent clotting. So you are prone to having blood clots and are at risk of clots forming in deep veins or clots traveling to the lungs and blocking blood flow.
  • High blood pressure. The buildup of wastes in your bloodstream (uremia) and salt retention can raise your blood pressure.
  • Infections. You are at increased risk of infections because you lose proteins in the urine that protect you from infection.
  • Nephrotic syndrome. This is a group of signs and symptoms that may accompany conditions that affect the filtering ability of the glomeruli. Nephrotic syndrome is characterized by high protein levels in the urine, low protein levels in the blood, high blood cholesterol, and swelling (edema) of the eyelids, feet and abdomen.
  • Acute kidney failure. In severe cases of damage to the glomeruli, waste products may build up quickly in your blood. You may need emergency dialysis to remove extra fluids and waste from your blood.
  • Chronic kidney failure. Your kidneys may gradually lose their function over time to the point where you may require dialysis or a kidney transplant.
Oct. 12, 2011