Acute liver failure often causes complications, including:
July 10, 2014
- Excessive fluid in the brain (cerebral edema). Excessive fluid causes pressure to build in your brain, which can displace brain tissue outside of the space it normally occupies (herniation). Cerebral edema can also deprive your brain of oxygen.
- Bleeding and bleeding disorders. A failing liver isn't able to produce sufficient amounts of clotting factors, which help blood to clot. People with acute liver failure often develop bleeding from the gastrointestinal tract. Bleeding may be difficult to control.
- Infections. People with acute liver failure are at an increased risk of developing a variety of infections, particularly in the blood and in the respiratory and urinary tracts.
- Kidney failure. Kidney failure often occurs following liver failure, especially in cases of acetaminophen overdose, which damages both your liver and your kidneys.
- Goldberg E, et al. Acute liver failure in adults: Etiology, clinical manifestations and diagnosis. http://www.uptodate.com/home. Accessed March 31, 2014.
- Goldberg E, et al. Acute liver failure in adults: Management and prognosis. http://www.uptodate.com/home. Accessed March 31, 2014.
- An introduction to liver care. American Liver Foundation. http://www.liverfoundation.org/education/downloads/. Accessed March 31, 2014.
- Acute liver failure. National Institutes of Health. http://livertox.nih.gov/Phenotypes_fail.html. Accessed March 31, 2014.
- Bernal W, et al. Acute liver failure. New England Journal of Medicine. 2013;369:2525.