Mayo Clinic has a long history of important contributions to advances in the diagnosis and treatment of liver disease. In fact, Mayo Clinic scientists and physicians publish more than 200 original gastroenterology and hepatology-related research articles every year.
Mayo Clinic researchers have pioneered new treatments of many liver diseases, as well as a new generation of endoscopes to perform incision-free, minimally invasive procedures for liver disease and other conditions.
Examples of Mayo's contributions, past and present, to liver disease diagnosis and treatment include:
Apr. 16, 2011
- Mayo researchers are testing hepatocyte transplantation, which involves the transfer of normal liver cells into a diseased liver.
- Mayo researchers are studying exciting new treatments such as gene therapy, in which physicians treat a disorder by inserting a missing gene into a patient's cells instead of using drugs or surgery.
- Mayo Clinic researchers are studying new treatments for primary oxalosis, a genetic liver disease, at the Hyperoxaluria Center in Minnesota.
- Mayo participates in research on hereditary hemochromatosis, and collects blood and tissue samples from patients for a patient registry for genetic research.
- Mayo Clinic doctors published the first clinical description of alpha-1 antitrypsin deficiency, a genetic liver disease.
- Your liver. Your life. What everybody needs to know about liver wellness. American Liver Foundation. http://www.yourliver.org/Liver-Wellness-Presentation.pdf. Accessed Feb. 24, 2011.
- Viral hepatitis: A through E and beyond. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/viralhepatitis/index.htm. Accessed Feb. 24, 2011.
- Cirrhosis. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/cirrhosis/index.htm. Accessed Feb. 24, 2011.
- It's dangerous to ignore your liver. American Liver Foundation. http://www.yourliver.org/risk.html. Accessed Feb. 24, 2011.
- Liver biopsy. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/liverbiopsy/index.htm. Accessed Feb. 24, 2011.
- Know your ALT. American Association for the Study of Liver Diseases. http://www.aasld.org/patients/Pages/KnowYourALT.aspx. Accessed Feb. 24, 2011.
- Pratt DS. Liver chemistry and function tests. In: Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4160-6189-2..X0001-7--TOP&isbn=978-1-4160-6189-2&about=true&uniqId=229935664-2192. Accessed Feb. 24, 2011.
- Seeff LB. Herbal hepatotoxicity. Clinics in Liver Disease. 2007;11:577.