Left ventricular hypertrophy changes both the structure and function of the chamber:
- The enlarged muscle loses elasticity and stiffens, preventing the chamber from filling properly and leading to increased pressure in the heart.
- The enlarged muscle tissue compresses its own blood vessels (coronary arteries) and may restrict its own supply of blood.
- The overworked muscle weakens.
Complications that can occur as a result of these problems include:
July 18, 2012
- Inability of your heart to pump enough blood to your body (heart failure)
- Abnormal heart rhythm (arrhythmia)
- Insufficient supply of oxygen to the heart (ischemic heart disease)
- Interruption of blood supply to the heart (heart attack)
- Sudden, unexpected loss of heart function, breathing and consciousness (sudden cardiac arrest)
- Douglas PS, et al. Definition and pathogenesis of left ventricular hypertrophy in hypertension. http://www.uptodate.com/index. Accessed May 28, 2012.
- Kaplan NM, et al. Clinical implications and treatment of left ventricular hypertrophy in hypertension. http://www.uptodate.com/ index. Accessed May 28, 2012.
- Katholi RE, et al. Left ventricular hypertrophy: Major risk factor in patients with hypertension — Update and practical clinical applications. International Journal of Hypertension. 2011;495349:1.
- Lorell BH, et al. Left ventricular hypertrophy: Pathogenesis, detection, and prognosis. Circulation. 2000;102:470.
- Rawlins J, et al. Left ventricular hypertrophy in athletes. European Journal of Echocardiography. 2009;10:350.
- Artham SM, et al. Clinical impact of left ventricular hypertrophy and implications for regression. Progress in Cardiovascular Diseases. 2009;52:153.
- What is high blood pressure? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/hbp/. Accessed May 30, 2012.
- Aortic valve stenosis (AS) and aortic insufficiency (AI). American Heart Association. http://www.heart.org/HEARTORG/Conditions/CongenitalHeartDefects/AboutCongenitalHeartDefects/Aortic-Valve-Stenosis-AVS_UCM_307020_Article.jsp. Accessed May 30, 2012.
- Gersh BJ, et al. 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2011;124:e783.
You Are ... The Campaign for Mayo Clinic
Mayo Clinic is a not-for-profit organization. Make a difference today.