Treatment at Mayo Clinic

By Mayo Clinic Staff


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Although there is no cure for Klippel-Trenaunay syndrome, Mayo Clinic experts can help you manage your symptoms and prevent complications. You and your doctor can work together to determine which of the following treatments are most appropriate for you:

  • Compression therapy. Bandages or elastic garments are wrapped around affected limbs to help prevent swelling, varicose veins and skin ulcers. Intermittent pneumatic compression devices — leg or arm sleeves that automatically inflate and deflate at set intervals — may be used.
  • Lifestyle management. Orthopedic shoes may improve your health and physical function.
  • Physical therapy. Massage, compression and encouraging use of the limb as appropriate may help relieve swelling in your arms or legs (lymphedema) and swelling of the blood vessels.
  • Epiphysiodesis (ep-ih-fiz-e-OD-uh-sis). This is an orthopedic procedure that effectively can stop overgrowth of the lower limb.
  • Embolization. This procedure, performed through small catheters placed into the veins or arteries, blocks blood flow to certain blood vessels.
  • Laser therapy. This procedure may lighten or eliminate port-wine stains on your skin.
  • Laser or radiofrequency ablation of veins. This minimally invasive procedure is used to close off abnormal veins.
  • Sclerotherapy. Your doctor injects a solution into your vein, which creates scar tissue that helps close the vein.
  • Placement of a vena cava filter. This procedure prevents blood clots from traveling to your lungs.
  • Surgery. In some cases, you may benefit from removal or reconstruction of your affected veins and correction of the overgrowth of bone.

In addition, you may need treatment for complications such as bleeding, infection, blood clots or skin ulcers.

Early research indicates that a drug called sirolimus may help prevent the growth of vascular malformations, but it may have significant side effects and more studies are needed.

Sept. 17, 2015