Diagnosis of Klippel-Trenaunay syndrome begins with a physical exam. Referral to a vascular specialist is helpful for evaluation and treatment recommendations. During the evaluation your doctor:
- Asks you questions about your family and medical history
- Examines you for swelling, varicose veins and port-wine stains
- Visually evaluates growth of your bones and soft tissues
Several diagnostic tests can help your doctor evaluate and determine the type and severity of your condition:
Sept. 17, 2015
- Duplex scanning. This test uses high-frequency sound waves to create detailed images of your blood vessels.
- Scanogram. Also called scanner photography, this X-ray technique helps your doctor see images of your bones and measure their lengths.
- Magnetic resonance angiography. This procedure helps your doctor differentiate between bone, fat, muscle and blood vessels.
- CT scan. A CT scan creates 3-D images of your body that help your doctor look for blood clots in veins.
- Contrast venography. This procedure involves injecting a dye into your veins and taking X-rays that can reveal abnormal veins, blockages or blood clots.
- Klippel-Trenaunay syndrome. Genetics Home Reference. http://ghr.nlm.nih.gov/condition/klippel-trenaunay-syndrome. Accessed July 24, 2015.
- Klippel-Trenaunay syndrome. National Organization for Rare Diseases. https://rarediseases.org/rare-diseases/klippel-trenaunay-syndrome/. Accessed July 27, 2015.
- Malgor RD, et al. Surgical treatment of varicose veins and venous malformations in Klippel-Trenaunay syndrome. Phlebology. In press. http://phl.sagepub.com/content/early/2015/03/17/0268355515577322.abstract. Accessed July 27 2015.
- Sharma D, et al. Klippel-Trenaunay syndrome — A very rare and interesting syndrome. Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine. 2015;9:1.
- NINDS Klippel-Trenaunay syndrome (KTS) information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/klippel_trenaunay/klippel_trenaunay.htm. Accessed July 27, 2015.
- AskMayoExpert. Klippel-Trenaunay syndrome. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2014.
- Colletti G, et al. Adjuvant role of anti-angiogenic drugs in the management of head and neck arteriovenous malformations. Medical Hypotheses. 2015;85:298.
- Gloviczki P (expert opinion). Mayo Clinic, Rochester, Minn. Aug. 16, 2015.
- Driscoll DJ (expert opinion). Mayo Clinic, Rochester, Minn. Aug. 26, 2015.