Research

As an international leader in kidney cancer research, Mayo Clinic researchers follow up on clinical outcomes and conduct research on all stages of kidney disease, to improve surgical techniques and the treatment of advanced disease with novel drug therapies. Eligible patients have a chance to enroll in clinical trials of Mayo and the National Cancer Institute to try the latest treatment innovations.

Benefits of surgery for late-stage cancer

Mayo Clinic researchers found that surgery significantly increased life expectancy for many patients with late-stage kidney cancer. Renal cell carcinoma patients who had surgery to completely remove secondary tumor growth, called metastases, had significantly improved survival compared with patients with metastases who did not have the surgery. This research confirms the importance of complete removal of the metastases, when possible, to prolong life.

Another Mayo study will evaluate the interaction of surgery and drugs to determine if the combination increases survival even more in people with late-stage kidney cancer whose cancer has spread.

Mayo Clinic research resources

Kidney cancer research is conducted in coordination with Mayo Clinic Cancer Center. The Mayo Clinic Cancer Center receives funding from the National Cancer Institute and is designated as a comprehensive cancer center — recognition for an institution's scientific excellence and multidisciplinary resources focused on cancer prevention, diagnosis and treatment.

The Mayo Clinic Biobank database, one of the largest in the world, provides samples for studies on kidney cancer and other diseases. The Cancer Immunology and Immunotherapy Program of the Mayo Clinic Cancer Center studies the mechanisms involved in cancer development and how the immune system responds to cancer. The program also develops and tests immune therapies for cancer patients.

Publications

See a list of publications by Mayo Clinic authors on kidney cancer on PubMed, a service of the National Library of Medicine.