Your risk of developing iritis increases if you:

  • Have a specific genetic alteration. People with HLA-B27, a specific change in a gene that's essential for healthy immune system function, are more likely to develop iritis.
  • Develop a sexually transmitted infection. Certain infections, such as syphilis or HIV/AIDs, are linked with a significant risk of iritis.
  • Live in certain geographic locations where infectious causes are more prevalent, for instance, in the U.S. in the Ohio or Mississippi river valleys where histoplasmosis — a fungal infection — occurs more frequently.
  • Have a compromised immune system or autoimmune disorder.
Feb. 14, 2014