Symptoms and causes


The signs and symptoms of interstitial cystitis vary from person to person. If you have interstitial cystitis, your symptoms may also vary over time, periodically flaring in response to common triggers, such as menstruation, sitting for a long time, stress, exercise and sexual activity.

Interstitial cystitis signs and symptoms include:

  • Pain in your pelvis or between the vagina and anus in women
  • Pain between the scrotum and anus in men (perineum)
  • Chronic pelvic pain
  • A persistent, urgent need to urinate
  • Frequent urination, often of small amounts, throughout the day and night (up to 60 times a day)
  • Pain or discomfort while the bladder fills and relief after urinating.
  • Pain during sexual intercourse.

Symptoms severity is different for everyone, and some people may experience symptom-free periods.

Although signs and symptoms of interstitial cystitis may resemble those of a chronic urinary tract infection, there's usually no infection. However, symptoms may worsen if a person with interstitial cystitis gets a urinary tract infection.

When to see a doctor

If you're experiencing chronic bladder pain or urinary urgency and frequency, contact your doctor.


The exact cause of interstitial cystitis isn't known, but it's likely that many factors contribute. For instance, people with interstitial cystitis may also have a defect in the protective lining (epithelium) of the bladder. A leak in the epithelium may allow toxic substances in urine to irritate your bladder wall.

Other possible but unproven contributing factors include an autoimmune reaction, heredity, infection or allergy.

Risk factors

These factors are associated with a higher risk of interstitial cystitis:

  • Your sex. Women are diagnosed with interstitial cystitis more often than men. Symptoms in men may mimic interstitial cystitis, but they're more often associated with an inflammation of the prostate gland (prostatitis).
  • Your skin and hair color. Having fair skin and red hair has been associated with a greater risk of interstitial cystitis.
  • Your age. Most people with interstitial cystitis are diagnosed during their 30s or older.
  • Having a chronic pain disorder. Interstitial cystitis may be associated with other chronic pain disorder, such as irritable bowel syndrome or fibromyalgia.


Interstitial cystitis can result in a number of complications, including:

  • Reduced bladder capacity. Interstitial cystitis can cause stiffening of the bladder wall, which allows your bladder to hold less urine.
  • Lower quality of life. Frequent urination and pain may interfere with social activities, work and other activities of daily life.
  • Sexual intimacy problems. Frequent urination and pain may strain your personal relationships, and sexual intimacy may suffer.
  • Emotional troubles. The chronic pain and interrupted sleep associated with interstitial cystitis may cause emotional stress and can lead to depression.
Oct. 11, 2016
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