Below are current clinical trials.1 studies in Indigestion
(open studies only).
Filter this list of studies by location, status and more.
A Study of Motilitone to Treat Functional Dyspepsia
Study type: Interventional What is this?
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study phase: II What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.
About this study
This study is to evaluate the effectiveness of the investigational drug motilitone at 90 mg in patients with functional dyspepsia as measured by change in maximum tolerated volume and the aggregate symptom score on the nutrient drink test.
Participating Mayo Clinic locations
Study statuses change often. Please contact us for help.
Print study details
- Rochester, Minnesota: 14-006861
NCT ID: NCT02365701
Sponsor Protocol Number: 14-006861
Aug. 24, 2016
- Feldman M, et al. Dyspepsia. In: Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 10th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. http://www.clinicalkey.com. Accessed Jan. 6, 2016.
- Talley MJ, et al. Functional Dyspepsia. New England Journal of Medicine. 2015;373:1852.
- Indigestion. National Digestive Diseases Information Clearinghouse. http://digestive.niddk.nih.gov/ddiseases/pubs/indigestion/index.aspx. Accessed Jan. 28, 2016.
- Papadakis MA, et al., eds. Gastrointestinal disorders. In: Current Medical Diagnosis & Treatment 2015. 54th ed. New York, N.Y.: The McGraw-Hill Companies; 2015. http://www.accessmedicine.com. Accessed Jan. 28, 2016.
- Dyspepsia. Merck Manual Professional Version. http://www.merckmanuals.com/professional/print/gastrointestinal_disorders/approach_to_the_patient_with_upper_gi_complaints/dyspepsia.html. Accessed Jan. 28, 2016.
- Overland MK. Dyspepsia. Medical Clinics of North America. 2014;98:549.
- Ottillinger B, et al. STW 5 (Iberogast) — A safe and effective standard in the treatment of functional gastrointestinal disorders. Wiener Medizinische Wochenschrift. 2013;163:65.
- Aucoin M, et al. Mindfulness-based therapies in the treatment of functional gastrointestinal disorders: A meta-analysis. Evidence-Based Complementary and Alternative Medicine. 2014;2014:1.
- Kim KN, et al. Efficacy of acupuncture treatment for functional dyspepsia: A systematic review and meta-analysis. Complementary Therapies in Medicine. 2015;23:759.