Indigestion has many possible causes. Often, indigestion is related to lifestyle and may be triggered by food, drink or medication. Common causes of indigestion include:
- Overeating or eating too quickly
- Fatty, greasy or spicy foods
- Too much caffeine, alcohol, chocolate or carbonated beverages
- Certain antibiotics, pain relievers and iron supplements
Sometimes indigestion is caused by other digestive conditions, including:
- Peptic ulcers
- Celiac disease
- Pancreas inflammation (pancreatitis)
- Stomach cancer
- Intestinal blockage
- Reduced blood flow in the intestine (intestinal ischemia)
Indigestion with no obvious cause is known as functional dyspepsia or nonulcer stomach pain.
May. 01, 2013
- Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4160-6189-2..X0001-7--TOP&isbn=978-1-4160-6189-2&about=true&uniqId=229935664-2192. Accessed Feb. 25, 2013.
- AskMayoExpert. What is the recommended work-up for a patient with dyspepsia? Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2012.
- Indigestion. National Digestive Diseases Information Clearinghouse. http://digestive.niddk.nih.gov/ddiseases/pubs/indigestion/index.aspx. Accessed Feb. 25, 2013.
- Papadakis MA, et al. Current Medical Diagnosis & Treatment 2013. 52nd ed. New York, N.Y.: The McGraw-Hill Companies; 2013. http://www.accessmedicine.com/resourcetoc.aspx?resourceid=1. Accessed Feb. 25, 2013.
- Dyspepsia. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/print/gastrointestinal_disorders/approach_to_the_patient_with_upper_gi_complaints/dyspepsia.html. Accessed Feb. 26, 2013.
- Lacy BE, et al. Review article: Current treatment options and management of functional dyspepsia. Alimentary Pharmacology & Therapeutics. 2012;36:3.
- Camilleri M, et al. Current management strategies and emerging treatments for functional dyspepsia. Nature Reviews Gastroenterology & Hepatology. In press. Accessed Feb. 26, 2013.
- Zeng F, et al. Influence of acupuncture treatment on cerebral activity in functional dyspepsia patients and its relationship with efficacy. American Journal of Gastroenterology. 2012;107:1236.
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