Below are current clinical trials.4 studies in Hyperoxaluria and oxalosis
(open studies only).
Filter this list of studies by location, status and more.
This study is being done to obtain samples from patients with primary hyperoxaluria, cystinuria, adenine phosphoribosyl transferase (APRT) deficiency, and Dent disease, and from their family members, for use in future research.
Evaluate the safety, tolerability, and efficacy of 28 days of treatment with ALLN-177 for reducing urinary oxalate excretion in patients with secondary hyperoxaluria and kidney stones.
The purpose of this study is to assess for elevated levels of calcium oxalate in the urine and kidney stones, in patients who have had gastric bypass surgery for obesity.
The purpose of this study is to learn more about a condition called 'unclassified hyperoxaluria'. People with this condition have large amounts of oxalate (a salt) in their urine, which can cause kidney stones and kidney failure. We do not know what causes the high level of oxalate in the urine. In this study, we will examine how oxalate in the diet affects this condition. We will compare the results of affected patients to healthy volunteers.
May 14, 2016
- Primary hyperoxaluria. Genetics Home Reference — National Institutes of Health. http://ghr.nlm.nih.gov/condition/primary-hyperoxaluria. Accessed Feb. 11, 2016.
- Learn more — Primary hyperoxaluria (PH). Rare Kidney Stone Consortium. http://www.rarediseasesnetwork.org/RKSC/PH/. Accessed Feb. 11, 2016.
- Niaudet P. Primary hyperoxaluria. http://www.uptodate.com/home. Accessed Feb. 11, 2016.
- Bope ET, et al. Renal calculus. In: Conn's Current Therapy 2016. Philadelphia, Pa.: Elsevier; 2016. http://www.clinicalkey.com. Accessed Feb. 24, 2016.
- What I need to know about kidney stones. National Kidney and Urologic Diseases Information Clearinghouse. http://www.niddk.nih.gov/health-information/health-topics/urologic-disease/kidney-stones-in-adults/Pages/ez.aspx. Accessed Feb. 11, 2016.
- Hoppe B. An update on primary hyperoxaluria. Nature Reviews Nephrology. 2012;8:467.
- Carrasco A, et al. Surgical management of stone disease in patients with primary hyperoxaluria. Urology. 2015;85:522.
- What are the signs of kidney failure? Urology Care Foundation. http://www.urologyhealth.org/urologic-conditions/kidney-(renal)-failure/symptoms. Accessed Feb. 22, 2016.
- Pearle MS, et al. Medical management of kidney stones: AUA guideline. The Journal of Urology. 2014;192:316.
- Lieske JC (expert opinion). Mayo Clinic, Rochester, Minn. April 21, 2016.
Hyperoxaluria and oxalosis