HIV is a viral infection that can be transmitted through sexual contact, through blood or from mother to child during pregnancy, childbirth or breast-feeding.
How does HIV become AIDS?
HIV destroys CD4 cells — a specific type of white blood cell that plays a large role in helping your body fight disease. Your immune system weakens as more CD4 cells are killed. You can have an HIV infection for years before it progresses to AIDS.
People infected with HIV progress to AIDS when their CD4 count falls below 200 or they experience an AIDS-defining complication.
How HIV is transmitted
To become infected with HIV, infected blood, semen or vaginal secretions must enter your body. You can't become infected through ordinary contact — hugging, kissing, dancing or shaking hands — with someone who has HIV or AIDS. HIV can't be transmitted through the air, water or insect bites.
You can become infected with HIV in several ways, including:
July 21, 2015
- By having sex. You may become infected if you have vaginal, anal or oral sex with an infected partner whose blood, semen or vaginal secretions enter your body. The virus can enter your body through mouth sores or small tears that sometimes develop in the rectum or vagina during sexual activity.
- From blood transfusions. In some cases, the virus may be transmitted through blood transfusions. American hospitals and blood banks now screen the blood supply for HIV antibodies, so this risk is very small.
- By sharing needles. HIV can be transmitted through needles and syringes contaminated with infected blood. Sharing intravenous drug paraphernalia puts you at high risk of HIV and other infectious diseases, such as hepatitis.
- During pregnancy or delivery or through breast-feeding. Infected mothers can infect their babies. But by receiving treatment for HIV infection during pregnancy, mothers significantly lower the risk to their babies.
- Longo DL, et al., eds. Human immunodeficiency virus disease. In: Harrison's Principles of Internal Medicine. 19th ed. New York, N.Y.: The McGraw-Hill Companies; 2015. http://accessmedicine.com. Accessed June 3, 2015.
- What is HIV? AIDS.gov. http://www.aids.gov/hiv-aids-basics/. Accessed June 3, 2015.
- Sax PE. Acute and early HIV infection: Clinical manifestations and diagnosis. http://www.uptodate.com/home. Accessed June 3, 2015.
- Bartlett JG. The natural history and clinical history of HIV infection in adults and adolescents. http://www.uptodate.com/home. Accessed June 3, 2015.
- Ferri FF. Human immunodeficiency virus. In: Ferri's Clinical Advisor 2015: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2015. https://www.clinicalkey.com. Accessed June 3, 2015.
- HIV/AIDS. National Institute of Allergy and Infectious Diseases. http://www.niaid.nih.gov/topics/hivaids/understanding/Pages/Default.aspx. Accessed June 3, 2015.
- Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents. National Institutes of Health. https://aidsinfo.nih.gov/guidelines/html/4/adult-and-adolescent-oi-prevention-and-treatment-guidelines/0. Accessed June 5, 2015.
- Pollack TM, et al. Primary care of HIV-infected adults. http://www.uptodate.com/home. Accessed June 3, 2015.
- Natural medicines in the clinical management of HIV/AIDS. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed June 3, 2015.
- Pre-exposure prophylaxis (PrEP). AIDS.gov. https://www.aids.gov/hiv-aids-basics/prevention/reduce-your-risk/pre-exposure-prophylaxis/index.html. Accessed June 3, 2015.
- Lower your sexual risk of HIV. AIDS.gov. https://www.aids.gov/hiv-aids-basics/prevention/reduce-your-risk/sexual-risk-factors/. Accessed June 3, 2015.