Niacin overdose is unlikely if you take niacin only in the amount prescribed by your doctor. While it's not possible to overdose on niacin simply by eating too many niacin-rich foods, taking too much over-the-counter or prescription niacin can be dangerous.
Niacin overdose signs and symptoms include:
- Severe skin flushing combined with dizziness
- Rapid heartbeat
- Nausea and vomiting
- Abdominal pain
If you think you may have overdosed, seek medical attention immediately.
Because niacin has also been linked to liver damage and stroke, most doctors now recommend it only for people who can't take statins to treat high triglyceride levels. If you're concerned about taking niacin, talk to your doctor.
Dec. 11, 2014
- Toth PP, et al. Niacin extended-release/simvastatin combination therapy produces larger favorable changes in high-density lipoprotein particles than atorvastatin monotherapy. Vascular Health and Risk Management. 2012;8:39.
- Arcinegas-Rodriguez S, et al. Metabolic acidosis, hypoglycemia, and severe myalgias: An attempt to mask urine drug screen results. Pediatric Emergency Care. 2011;27:315.
- Daul AM, et al. Niacin toxicity resulting from urine drug test evasion. The Journal of Emergency Medicine. 2011;41:e65.
- AskMayoExpert. Niacin therapy. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2013.