Signs and symptoms of hemophilia vary, depending on your level of clotting factors. If your clotting-factor level is mildly reduced, you may bleed only after surgery or trauma. If your deficiency is severe, you may experience spontaneous bleeding.
Signs and symptoms of spontaneous bleeding include:
- Unexplained and excessive bleeding from cuts or injuries, or after surgery or dental work
- Many large or deep bruises
- Unusual bleeding after vaccinations
- Pain, swelling or tightness in your joints
- Blood in your urine or stool
- Nosebleeds without a known cause
- In infants, unexplained irritability
Emergency signs and symptoms of hemophilia include:
- Sudden pain, swelling and warmth in large joints, such as knees, elbows, hips and shoulders, and in your arm and leg muscles
- Bleeding from an injury, especially if you have a severe form of hemophilia
- Painful, prolonged headache
- Repeated vomiting
- Extreme fatigue
- Neck pain
- Double vision
When to see a doctor
Prolonged bleeding after circumcision may be the first indication of hemophilia in a baby boy. In boys who aren't circumcised, easy bruising when the child becomes more mobile may lead to the diagnosis. The first episode of bleeding generally occurs by the time a child is 2 years old.
If your child bruises easily, see your doctor. If your child has heavy bleeding that can't be stopped after an injury, seek emergency medical care.
If you're pregnant or considering pregnancy, and have a family history of hemophilia, talk to your doctor. You may be referred to a specialist in medical genetics or bleeding disorders, who can help you determine if you are a carrier of hemophilia. If you are a carrier, it's possible to determine during pregnancy if the fetus is affected by hemophilia.
Sep. 11, 2014
- Hoots WK, et al. Clinical manifestations and diagnosis of hemophilia. http://www.uptodate.com/home. Accessed May 12, 2014.
- AskMayoExpert. What tests are needed to confirm the diagnosis or expedite the evaluation of hemophilia? Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2014.
- Hoffman R, et al. Hematology: Basic Principles and Practice. 6th ed. Philadelphia, Pa.: Saunders Elsevier 2013. http://www.clinicalkey.com. Accessed May 12, 2014.
- Kliegman RM, et al. Nelson Textbook of Pediatrics. 19th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.clinicalkey.com. Accessed May 12, 2014.
- Hoots WK, et al. Treatment of hemophilia. http://www.uptodate.com/home. Accessed May 12, 2014.
- Berntorp E, et al. Modern haemophilia care. The Lancet. 2012;379:1447.
- Living with hemophilia. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/hemophilia/livingwith.html Accessed May 13, 2014.
- Lim MY, et al. Outcomes of management of acute coronary syndrome in patients with congenital bleeding disorders: A single center experience and review of the literature. Thrombosis Research. 2012;130:316.
- Barbara Woodward Lips Patient Education Center. Hemophilia. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2009.
- Cook, AJ. Decision Support System. Mayo Clinic, Rochester, Minn. July 17, 2014.
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